Arc and Memory

by F.

Physorg.com digests a recent paper from Neuron:

Researchers at Johns Hopkins have figured out how one particular protein contributes to long-term memory and helps the brain remember things longer than an hour or two. The findings are reported in two papers in the Nov. 9 issue of Neuron.

The protein, called Arc, has been implicated in memory-linked behaviors ranging from song learning in birds to rodents being aware of 3-D space. In people, Arc may be one culprit behind certain long-term memory-based behaviors like drug addiction, the researchers say.

“We think Arc controls how brain cells learn and associate behaviors and remember them over a long period of time,” says Paul F. Worley, M.D., professor of neuroscience and neurology at Hopkins and director of both studies. “For example, the person who quits smoking can wean himself from cravings at home, at work or outside. But if you put him in a bar with a drink in his hand, his brain remembers that former association and suddenly the craving returns. These types of long-term associations are memories wired in your brain.”

The rest.

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